Characterization of α-tocopherol-loaded MCM-41 mesoporous silica with different pore sizes and antioxidant active packaging films
Li-nan Sun
Department of Packaging Engineering, Jiangnan University, Wuxi, 214122 China
Search for more papers by this authorCorresponding Author
Li-xin Lu
Department of Packaging Engineering, Jiangnan University, Wuxi, 214122 China
Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment and Technology, Wuxi, 214122 China
Correspondence
Li-xin Lu, Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment and Technology, Wuxi 214122, China.
Email: lulx@jiangnan.edu.cn
Search for more papers by this authorLiao Pan
Department of Packaging Engineering, Jiangnan University, Wuxi, 214122 China
Search for more papers by this authorQing Wang
Beijing Vegetable Research Center, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097 China
Search for more papers by this authorXiao-lin Qiu
Department of Packaging Engineering, Jiangnan University, Wuxi, 214122 China
Search for more papers by this authorLi-nan Sun
Department of Packaging Engineering, Jiangnan University, Wuxi, 214122 China
Search for more papers by this authorCorresponding Author
Li-xin Lu
Department of Packaging Engineering, Jiangnan University, Wuxi, 214122 China
Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment and Technology, Wuxi, 214122 China
Correspondence
Li-xin Lu, Jiangsu Key Laboratory of Advanced Food Manufacturing Equipment and Technology, Wuxi 214122, China.
Email: lulx@jiangnan.edu.cn
Search for more papers by this authorLiao Pan
Department of Packaging Engineering, Jiangnan University, Wuxi, 214122 China
Search for more papers by this authorQing Wang
Beijing Vegetable Research Center, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097 China
Search for more papers by this authorXiao-lin Qiu
Department of Packaging Engineering, Jiangnan University, Wuxi, 214122 China
Search for more papers by this authorAbstract
Antioxidant active packaging films were prepared with low-density polyethylene (LDPE) being incorporated with α-tocopherol-loaded MCM-41 mesoporous silica. In order to study the influence of pore size and morphology of the mesoporous material on physical and release properties of films, the mesoporous materials were synthesized with various pore sizes and morphologies. MCM-41 mesoporous silica materials before and after being loaded with α-tocopherol were characterized, as well as the active films. The results show that physical properties and release profiles of active films can be changed when being incorporated with mesoporous materials with different structures: crystallinity of films prepared ranged from 11.30% to 18.13%, and the tendency of change was in good accordance with that of specific surface area of mesoporous silica materials. Variation of release rates of the antioxidant in packaging films can be achieved by changing MCM-41 pore size, and the release period can be prolonged by ~64% in the scope of this study. These demonstrate that LDPE/α-tocopherol/MCM-41 films with adjustable release profile and physical properties have the potential to be used as antioxidant active packaging films.
Supporting Information
Filename | Description |
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pts2540-sup-0001-Supporting information.docxWord 2007 document , 26 KB |
Data S1. Determination of the specific surface area, total pore volume and pore size of MCM-41 mesoporous silica S1.2 Total pore volume S1.3 Pore size |
Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
REFERENCES
- 1LaCoste A, Schaich KM, Zumbrunnen D, Yam KL. Advancing controlled release packaging through smart blending. Packag Technol Sci. 2005; 18: 77-87.
- 2Koontz J, Moffitt R, Marcy J, O'Keefe S, Duncan S, Long T. Controlled release of α-tocopherol, quercetin, and their cyclodextrin inclusion complexes from linear low-density polyethylene (LLDPE) films into a coconut oil model food system. Food Addit Contam. 2010; 27(11): 1598-1607.
- 3Koontz JL. Controlled Release of Natural Antioxidants from Polymer Food Packaging by Molecular Encapsulation with Cyclodextrins. Ph.D. thesis, Virginia Polytechnic Institute and State University, 2008.
- 4Siró I, Fenyvesi É, Szente L, et al. Release of alpha-tocopherol from antioxidative low-density polyethylene film into fatty food simulant: influence of complexation in beta-cyclodextrin. Food Addit Contam. 2006; 23(8): 845-853.
- 5Barba C, Eguinoa A, Maté JI. Preparation and characterization of β-cyclodextrin inclusion complexes as a tool of a controlled antimicrobial release in whey protein edible films. LWT—Food Sci Technol. 2015; 64(2): 1362-1369.
- 6Lashkari E, Wang H, Liu L, Li J, Yam K. Innovative application of metal-organic frameworks for encapsulation and controlled release of allyl isothiocyanate. Food Chem. 2017; 221: 926-935.
- 7Chopra S, Dhumal S, Abeli P, Beaudry R, Almenar E. Metal-organic frameworks have utility in adsorption and release of ethylene and 1-methylcyclopropene in fresh produce packaging. Postharvest Biol Technol. 2017; 130: 48-55.
- 8Niu B, Yan Z, Shao P, Kang J, Chen H. Encapsulation of cinnamon essential oil for active food packaging film with synergistic antimicrobial activity. Nanomaterials. 2018; 8(8): 598-615.
- 9Gargiulo N, Attianese I, Buonocore GG, et al. α-Tocopherol release from active polymer films loaded with functionalized SBA-15 mesoporous silica. Micropor Mesopor Mat. 2013; 167: 10-15.
- 10Stanzione M, Gargiulo N, Caputo D, et al. Peculiarities of vanillin release from amino-functionalized mesoporous silica embedded into biodegradable composites. Eur Polym J. 2017; 89: 88-100.
- 11Heirlings L, Siró I, Devlieghere* F, et al. Influence of polymer matrix and adsorption onto silica materials on the migration of alpha-tocopherol into 95% ethanol from active packaging. Food Addit Contam. 2004; 21(11): 1125-1136.
- 12Wu C, Zhu Y, Wu T, et al. Enhanced functional properties of biopolymer film incorporated with curcurmin-loaded mesoporous silica nanoparticles for food packaging. Food Chem. 2019; 288: 139-145.
- 13Sun L-N, Lu L-X, Qiu X-L, Tang Y-L. Development of low-density polyethylene antioxidant active films containing α-tocopherol loaded with MCM-41(Mobil Composition of Matter No. 41) mesoporous silica. Food Control. 2017; 71: 193-199.
- 14Sun L-N, Lu L-X, Wang L-Q, Qiu X-L, Ge C. Influence of α-tocopherol/MCM-41 assembly on physical and antioxidant release properties of low-density polyethylene antioxidant active films. Polym Eng Sci. 2018; 58(10): 1710-1716.
- 15Muriel-Galet V, Pérez-Esteve É, Ruiz-Rico M, et al. Anchoring gated mesoporous silica particles to ethylene vinyl alcohol films for smart packaging applications. Nanomaterials. 2018; 8(10): 865–879.
- 16Wu S-H, Mou C-Y, Lin H-P. Synthesis of mesoporous silica nanoparticles. Chem Soc Rev. 2013; 42(9): 3862-3875.
- 17Zhao D, Wan Y, Zhou W. Ordered Mesoporous Materials. New York: John Wiley & Sons; 2012 140p.
- 18Mehmood A, Ghafar H, Yaqoob S, Gohar U, Ahmad B. Mesoporous silica nanoparticles: a review. J Dev Drugs. 2017; 6(2): 1-14, 1000174.
10.4172/2329-6631.1000174 Google Scholar
- 19Vallet-Regí M, Balas F, Arcos D. Mesoporous materials for drug delivery. Angew Chem Int Ed. 2007; 46(40): 7548-7558.
- 20Qu F, Zhu G, Huang S, et al. Controlled release of captopril by regulating the pore size and morphology of ordered mesoporous silica. Micropor Mesopor Mat. 2006; 92(1-3): 1-9.
- 21Manzano M, Aina V, Arean C, et al. Studies on MCM-41 mesoporous silica for drug delivery: effect of particle morphology and amine functionalization. Chem Eng J. 2008; 137(1): 30-37.
- 22Mansouri S, Khiari R, Bettaieb F, Abou-Zeid RE, Malek F, Mhenni F. Characterization of composite materials based on LDPE loaded with agricultural Tunisian waste. Polym Compos. 2015; 36(5): 817-824.
- 23Crank J. The Mathematics of Diffusion. New York: Oxford University Press; 1975: 47-48p.
- 24Sing KS. Physisorption of gases by carbon blacks. Carbon. 1994; 32(7): 1311-1317.
- 25Sayari A, Yang Y, Kruk M, Jaroniec M. Expanding the pore size of MCM-41 silicas: use of amines as expanders in direct synthesis and postsynthesis procedures. J Phys Chem B. 1999; 103(18): 3651-3658.
- 26Schmidt R, Hansen EW, Stoecker M, Akporiaye D, Ellestad OH. Pore size determination of MCM-51 mesoporous materials by means of 1H NMR spectroscopy, N2 adsorption, and HREM. A preliminary study. J am Chem Soc. 1995; 117(14): 4049-4056.
- 27Sing KS. Reporting physisorption data for gas/solid systems with special reference to the determination of surface area and porosity (recommendations 1984). Pure Appl Chem. 1985; 57(4): 603-619.
- 28Beck JS, Vartuli JC, Roth WJ, et al. A new family of mesoporous molecular sieves prepared with liquid crystal templates. J am Chem Soc. 1992; 114(27): 10834-10843.
- 29Shah PV, Rajput SJ. A comparative in vitro release study of raloxifene encapsulated ordered MCM-41 and MCM-48 nanoparticles: a dissolution kinetics study in simulated and biorelevant media. J Drug Deliv Sci Technol. 2017; 41: 31-44.
- 30Solanki P, Patel S, Devkar R, Patel A. Camptothecin encapsulated into functionalized MCM-41: in vitro release study, cytotoxicity and kinetics. Mater Sci Eng C. 2019; 98: 1014-1021.
- 31Jesus RA, Rabelo AS, Figueiredo RT, et al. Synthesis and application of the MCM-41 and SBA-15 as matrices for in vitro efavirenz release study. J Drug Deliv Sci Technol. 2016; 31: 153-159.
- 32Jehng J-M, Tung W-C, Huang C-H, Wachs IE. Structural characteristics and reactivity properties of the tantalum modified mesoporous silicalite (MCM-41) catalysts. Micropor Mesopor Mat. 2007; 99(3): 299-307.
- 33Grün M, Unger KK, Matsumoto A, Tsutsumi K. Novel pathways for the preparation of mesoporous MCM-41 materials: control of porosity and morphology. Micropor Mesopor Mat. 1999; 27(2-3): 207-216.
- 34Olmos D, Rodríguez-Gutiérrez E, González-Benito J. Polymer structure and morphology of low density polyethylene filled with silica nanoparticles. Polym Compos. 2012; 33(11): 2009-2021.
- 35Ma W, Wang X, Zhang J. Effect of MMT, SiO2, CaCO3, and PTFE nanoparticles on the morphology and crystallization of poly(vinylidene fluoride). J Polym Sci B. 2010; 48(20): 2154-2164.
- 36Jafarzadeh Y, Yegani R, Tantekin-Ersolmaz SB. Effect of TiO2 nanoparticles on structure and properties of high density polyethylene membranes prepared by thermally induced phase separation method. Polym Adv Technol. 2015; 26(4): 392-398.
- 37Laird ED, Li CY. Structure and morphology control in crystalline polymer–carbon nanotube nanocomposites. Macromolecules. 2013; 46(8): 2877-2891.
- 38Zhang MQ, Rong MZ, Yu SL, Wetzel B, Friedrich K. Effect of particle surface treatment on the tribological performance of epoxy based nanocomposites. Wear. 2002; 253(9-10): 1086-1093.
- 39Soitong T, Pumchusak J. The relationship of crystallization behavior, mechanical properties, and morphology of polypropylene nanocomposite fibers. J Mater Sci. 2011; 46(6): 1697-1704.
- 40Wang N, Fang Q, Chen E, Shaohang J, Shao Y. Preparation and characterization of polypropylene composites filled with different structured mesoporous particles. J Compos Mater. 2010; 44(17): 2083-2093.
- 41Wang N, Shi Z-X, Zhang J, Wang L. The influence of modification of mesoporous silica with polyethylene via in situ Ziegler–Natta polymerization on PE/MCM-41 nanocomposite. J Compos Mater. 2008; 42(12): 1151-1157.
- 42Scarfato P, Avallone E, Galdi MR, Di Maio L, Incarnato L. Preparation, characterization, and oxygen scavenging capacity of biodegradable α-tocopherol/PLA microparticles for active food packaging applications. Polym Compos. 2017; 38(5): 981-986.
- 43Koontz JL, Marcy JE, O'Keefe SF, Duncan SE, Long TE, Moffitt RD. Polymer processing and characterization of LLDPE films loaded with α-tocopherol, quercetin, and their cyclodextrin inclusion complexes. J Appl Polym Sci. 2010; 117(4): 2299-2309.
- 44Lin OH, Akil HM, Mohd Ishak Z. Surface-activated nanosilica treated with silane coupling agents/polypropylene composites: mechanical, morphological, and thermal studies. Polym Compos. 2011; 32(10): 1568-1583.
- 45Wu CL, Zhang MQ, Rong MZ, Friedrich K. Tensile performance improvement of low nanoparticles filled–polypropylene composites. Compos Sci Technol. 2002; 62(10-11): 1327-1340.